2011 Accepted Abstract List

 

ACCEPTED ABSTRACTS FOR IGES CONFERENCE, HEIDELBERG, GERMANY

If your abstract is listed on these tables, your abstract has been accepted  for presentation.

ABSTRACTS ACCEPTED FOR PLATFORM PRESENTATION

 

Author Last Name

Title

Organization

Borecki

Detection and Dissection of Pleiotropy for Complex Multivariate Traits

Washington University in St. Louis

Chen

Two-phase Stratified Sampling Designs for Regional Sequencing

Samuel Lunenfeld Research Institute

Coassin

Investigation and Functional Characterization of Rare Genetic Variants in the Adipose Triglyceride Lipase (ATGL) in a Large Healthy Working Population

Division of Genetic Epidemiology, Innsbruck Medical University, Innsbruck, Austria

Dudbridge

Inferring the frequencies and effect sizes of unobserved causal variants by using the family history of cases

London School of Hygiene and Tropical Medicine

Edwards

Efficient capture of allele frequency spectra in resequencing studies by selection of independent chromosomes.

Center for Human Genetics Research, Vanderbilt University

Epstein

A Novel Permutation Strategy to Correct for Population Stratification in Case-Control Studies of Rare Variation

Emory University

Göring

Principal components analysis in expression profile studies: Application to gene discovery and eQTN detection in an LCL-based expression profile study on schizophrenia

Texas Biomedical Research Institute, San Antonio, TX, USA

Goddard

Rapid uptake and use of a pharmacogenomic test for colon cancer treatment

Kaiser Permanente Northwest

Gorlova

Derived SNP allele are more frequently used as a risk-associated variants in common human diseases

UT MD Anderson Cancer Center

Herold

Integrated Genome-Wide Pathway Association Analysis Using Parallel Computing

German Center for Neurodegenerative Diseases, DZNE Bonn, Germany

Hill

Integration and visualization of genetic and genomic data using a 3-D video game engine

Institute for Quantitative Biomedical Sciences, Dartmouth College, Hanover, NH USA

Ionita-Laza

On study designs for identification of rare disease variants in complex diseases

Columbia University

 

   

Li

A likelihood-based framework for de novo mutation detection in families for next-generation sequencing data

Department of Biostatistics University of Michigan

Liang

A Bayesian Analysis and Optimal Design for Association Studies Using Next-Generation Pooled Sequencing Data

University of Southern California

Lin

A General Framework for Detecting Disease Associations With Rare Variants in Sequencing Studies

University of North Carolina

Nothnagel

A framework to assess technology-specific error signatures in next-generation sequencing, with an application to the 1000 Genomes Project data

Institute of Medical Informatics and Statistics, Christian-Albrechts University, Kiel, Germany

Pendergrass

A Phenome-wide Exploration of Novel Genotype-Phenotype Associations and Pleiotropy using MetaboChip in the PAGE Study

Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville TN, USA

Sarnowski

Taking into account imprinting and maternal genotype effects facilitates detection of new genes

INSERM, U946, Paris, France

Satten

Adjusting Rare Variant Association Tests for Population Stratification Using the Stratification Score

Centers for Disease Control and Prevention

Thomas

A STATISTICAL FRAMEWORK FOR ENVIRONMENTAL EPIGENETICS

University of Southern California

 

FINALISTS FOR NEEL AND WILLIAMS AWARDS      
AUTHOR ABSTRACT TITLE AFFILIATION AWARD TYPE
Jaffe Significance analysis and statistical dissection of variably methylated regions Johns Hopkins University Williams Award
         
Quintana Incorporating Model Uncertainty in Detecting Rare Variants: The Bayesian Risk Index Dept. of Preventive Medicine, Division of Biostatistics, Univ. of Southern California Neel Award
Ried PSEA: Phenotype Set Enrichment Analysis - A new method for genome wide analysis of multiple phenotypes  Institute of Genetic Epidemiology, Helmholtz Zentrum München (HMGU), Germany. Williams Award
Schwantes-An Interpreting joint-SNP analysis results: when are two distinct signals really two distinct signals? Washington University School of Medicine Williams Award
Verdugo Graphical modeling reveals primary genes in the gene expression network linking smoking to atherosclerotic plaques Unité Mixte de Recherche (UMRS 937), INSERM Neel Award
Xing Robust methods for analyzing secondary phenotypes in case-control genetic association studies Boston University Neel Award

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ABSTRACTS ACCEPTED FOR POSTER PRESENTATION

 

Author Last Name

Title

Organization

Abbenhardt

Phospholipase A2G1B Polymorphisms and Risk of Colorectal Neoplasia

National Center for Tumor Diseases/German Cancer Research Center, Heidelberg, Germany

Abel

Admixture mapping by graphical modeling

Division of Genetic Epidemiology, University of Utah

Abo

Identifying the genetic variation of gene expression using gene sets: application towards PharmGKB Gene Sets

Mayo Clinic

Ahn

A novel statistical method for testing the association of rare variants in a case-parent trio design

National Institute of Health

Amos

Further studies of the genetic architecture of lung cancer.

UT MD Anderson Cancer Center

Andrews

Multifactor Dimensionality Reduction 3.0: Open-Source Software for Systems Genetics

Institute for Quantitative Biomedical Sciences, Dartmouth College, Hanover, NH USA

Arbeev

Trade-off in the effects of the APOE polymorphism on the ages at onset of CVD and cancer: Insights from the genetic stochastic process model

Duke University

Bady

Genetic structure and admixture of the Seychelles' population

University of Lausanne, Switzerland

Bailey

Evolutionary Genetics of Myoclonin1/EFHC1, a gene for Juvenile Myoclonic Epilepsy (JME).

Department of Epidemiology, UCLA; West/LA VA Epilepsy Center of Excellence, Epilepsy Genetics/Genomics Laboratories, Los Angeles

Baksh

A robust score test for family-based association studies of complex diseases with ordinal responses, interactions and missing parental genotypes

University of Reading

Balliu

Modeling the non-inherited maternal antigens e
ffect in multi-case families

Dep. of Medical Statistics and Bioinformatics, Leiden University Medical Centre

Barhdadi

Performance of different balancing score methods in case-control genetic association studies

Montreal Heart Institute, Research Centre

Baurecht

A simulation pipeline for genetic disease models

Department of Dermatology, Allergology and Venerology, University Hospital Schleswig-Holstein, Kiel

Becker

Imputation-free Meta-Analysis with YAMAS

German Center for Neurodegenerative Diseases, DZNE, Bonn

Bhattacharya

Application of a novel method for testing gene-gene interactions to genome-wide association studies of seven complex human diseases

Wellcome Trust Centre for Human Genetics

Blackburn

A step toward an integrated map of copy number variation and heritable gene expression through linkage of CNVs in multigenerational pedigrees

University of Texas Health Science Center at San Antonio department of Cellcular and Structural Biology

Boehringer

Regularized heritability estimation in multivariate traits

Leiden University Medical Center

Brisbin

Association testing in sequencing studies: Accommodating risk and protective variants

Mayo Clinic

Brossard

To what extent genotype imputations are able to identify causal variants in genome-wide association studies?

INSERM U946, Fondation Jean-Dausset-CEPH, Paris, France

Brugger

Confounding between Genomic Imprinting and Sex-specific Recombination Frequencies: Evaluation of Properties of the MOD Score-based Imprinting Test Statistic MOBIT in a Linkage Simulation Study

Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany

Buchanan

Forward-time Simulation of Linkage Disequilibrium across Two Populations using GenomeSIMLA

Vanderbilt University

Bull

Alternative Test Statistics for Sparse Data in Genome-wide Association and Whole-genome Sequencing Analysis

Samuel Lunenfeld Research Institute and Dalla Lana School of Public Health, University of Toronto

Buxbaum

Association of Adiponectin Plasma Levels in African Americans with SNPs from Two Arrays

Jackson State University

Cannon-Albright

A National Resource combining Genetic and Phenotypic data: the VA genealogy project

University of Utah School of Medicine

Cardin

Aggregating information within loci when testing the genome for associations.

University of California, San Francisco

Cattaert

Comparison of different methods for detecting gene-gene interactions in case-control data

Montefiore Institute and GIGA-R, University of Liège, Belgium

Chang

Ethanol Metabolizing Genes and Risk of Head and Neck Cancer: Preliminary Report

National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan

Chen

A Sequential Combined p-value Test for Multiple Hypothesis Testing and its Application in Significance Analysis in Genomic Studies

Division of Cancer Control and Population Sciences, National Cancer Institute

Chen

Massively parallel model selection for re-sequencing studies using GPU clusters

Division of Biostatistics, Department of Preventive Medicine, University of Southern California

Cobat

A major pleiotropic locus on chromosomal region 11p15 controls mycobacteria-triggered TNF production

McGill Center for the Study of Host Resistance, McGill University, Montreal, Canada

Cropp

Novel functional variants for serum uric acid and total serum bilirubin levels in an Irish population

Inherited Disease Research Branch, NHGRI, NIH

Curjuric

Interaction of oxidative stress pathway genes with particulate matter and tobacco smoke on the course of airflow obstruction during 11 years

Swiss Tropical and Public Health Institute SwissTPH, Basel, and University of Basel, Switzerland

Darabi

Single- and Multi-Locus Association Tests Incorporating Phenotype Heterogeneity

Karolinska Institutet

Deng

A Maximum Likelihood Approach to Prioritize SNPs for Interactions Using Variance per Genotype

Departments of Clinical Epidemiology & Biostatistics, McMaster University

Dizier

THE ANO3/MUC15 LOCUS IS ASSOCIATED WITH ECZEMA IN FAMILY SAMPLES ASCERTAINED THROUGH ASTHMATICS

Inserm U946, Paris, France

Duarte

SNP Effect Decomposition in Family Data using Mixed Models

University of Sao Paulo

Duffy

Some new analytic procedures in the Sib-pair statistical genetics package.

Queensland Institute of Medical Research

Egeland

Regression models for DNA-mixtures

Norwegian University of Life Sciences

Eny

Genome-wide association study (GWAS) of lactose consumption measured longitudinally identifies a novel variant 500kb downstream of the LCT gene region.

Program in Genetics and Genome Biology, The Hospital for Sick Children

Evangelou

Comparison of Methods for Enrichment Tests in Pathway Analysis

MRC-Biostatistics Unit, University of Cambridge

Evangelou

Bayesian Hierarchical Modelling of SNPs and Pathways for Identifying Associated Pathways

MRC-Biostatistics Unit, University of Cambridge,UK

Evans

Gene-based association study for Specific Language Impairment

The University of Chicago

Fang

Genome-Wide Association Study of Melanoma Progression and Blood Biomarkers

The University of Texas MD Anderson Cancer Center

Feitosa

Nonalcoholic fatty liver disease predicts coronary heart disease independent of overall obesity and insulin resistance in non-diabetics in the NHLBI Family Heart Study

Div Statistical Genomics, Washington Univ Sch Medicine, St Louis, MO

Flaquer

Why does linkage analysis often fail with complex diseases?

Ludwig Maximilians University München

Foraita

A Bayesian network approach for pathway analysis using the gene ontology database

Bremen Institute for Prevention Research and Social Medicine

Fridley

Sample selection study designs to follow-up GWAS signals with targeted sequencing

Mayo Clinic

Gagnon

Prioritized-GWAS based on linkage information identifies novel putative loci influencing coagulation

University of Toronto Dalla Lana School of Public Health, Canada

Gaye

ESPRESSO: Algorithm for realistic power analysis and sample size calculation

University of Leicester

Gorlov

Beyond comparing means: the usefulness of analyzing interindividual variation in gene expression for identifying genes associated with cancer risk and development

The University of Texas MD Anderson Cancer Center

Grace

Multi-ethnic fine-mapping of cis expression-QTLs with fixed-effect meta-analysis

The Wellcome Trust Centre For Human Genetics, Oxford University

Grady

An Ensemble Pipeline to Enable Detection of Epistasis in Genomic Data

Center for Human Genetics Research

Gusareva

Genome-wide epistasis screening for Crohn's disease.

Systems and Model, Montefiore Institute, University of Liège; GIGA-R, University of Liège

Habermann

PTGS1 and PTGS2 polymorphisms, fatty acid intake, and risk of colon and rectal cancer

DKFZ / NCT

Haldar

Association Mapping Of Multivariate Phenotypes Using Transmission Disequilibrium

Indian Statistical Institute

Haug

Glutathione peroxidase (GPX) tagSNPs: Associations with rectal cancer but not with colon cancer

National Center for Tumor Diseases / German Cancer Research Center (DKFZ), Heidelberg, Germany

Heid

To stratify or not to stratify: What can be learned from power considerations and a practical genome-wide search on sex-difference in the GIANT consortium

Regensburg University Medical Center, Department of Epidemiology and Preventive Medicine, Regensburg, Germany

Holzinger

Bloat control methods substantially reduce computation time for detecting gene x gene interactions in ATHENA

Vanderbilt University

Howey

EMIM: Estimation of Maternal, Imprinting and interaction effects using Multinomial modelling

Newcastle University

Huebner

Mixed effects Cox models for gene set analysis in lung cancer

Statistics, Michigan State University and Mayo Clinic

Jarick

Evaluating the role of reference models in copy number variation analyses

Philipps-University of Marburg

Kampert

Software Packages to Conduct a GWAS On Data from (Twin) Families: a Review.

Department of Biological Psychology, Vrije Universiteit Amsterdam. Mathematical Institute, Leiden University

Kazma

Power to Detect Gene-Environment Interactions Involving Rare Variants

Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California San Francisco

Kesselmeier

Comparison of count models regarding their ability to capture the relationship between genomic instability, methylation and expression in human hepatocellular carcinoma

University Hospital Heidelberg, Institute of Medical Biometry and Informatics

Khan

Rules for resolving Mendelian inconsistencies in nuclear pedigrees typed for two-allele markers

Department of Statistics, Islamia College University, Peshawar

Kirdwichai

A non-parametric regression approach to the analysis of genomewide association studies

University of Reading

Kitajima

Smoking modifies the effect of lipoprotein lipase gene polymorphism on serum HDL-C concentration in Japanese general population.

Division of Genome Analysis, Research Center for Genetic Information, Medical Institute of Bioregulation, Kyushu University

Kraja

Are Studied Phenotypes up to the Next Generation Sequencing Challenge?

Div. of Statistical Genomics, Washington U. Sch. of Medicine, St. Louis, MO

Kuenzel

Parameter Estimation and Quantitative Parametric Linkage Analysis with GENEHUNTER-QMOD

Institute of Medical Biometry and Epidemiology, Philipps University Marburg

Kulminski

Complex modalities of gene action on phenotypes with post reproductive manifestation: the case of genetic trade-off

Duke University

Kulminski

Heritable Late Life Phenotypes and Inter-Chromosomal Linkage Disequilibrium in the Human Genome

Duke University

Kumasaka

PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data

Center for Genomic Medicine, RIKEN

Larribe

Modeling the history of a sample of genotypes.

UQAM

 

   

Leal

Estimating Genetic Effects and Quantifying Missing Heritability for Rare Variant Complex Trait Association Studies via Sequence Data

Baylor College of Medicine & Rice University

Lecarpentier

Effect of reproductive factors and body mass index on the mutation localization-specific risk of breast cancer in the French National BRCA1/2 carrier cohort (GENEPSO)

INSERM U900 Institut Curie-Inserm/Mines ParisTech

Li

SimRare: A program to generate and analyze sequence-based data for association studies of quantitative and qualitative traits

Baylor College of Medicine, Rice University

Li

A powerful and flexible framework for rare-variant analysis

Cedars-Sinai Medical Center

Li

Evaluation of methods to detect GXG interaction in case-parent trio data

Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health

Liang

Association of genetic variants with the risk of dysplastic nevi in melanoma-prone families with and without CDKN2A/CDK4 mutations

Division of Epidemiology, CDRH, Food and Drug Administration

Ling

Quality control and assurance strategies to optimize variant calling/detection using next generation sequencing (NGS) data

Center for Inherited Disease Research

Lippert

FaST Linear Mixed Models for Genome-Wide Association Studies

Microsoft Research and Max Planck Institutes Tuebingen

Liu

A unifying framework for analyzing rare variant quantitative trait associations in selected samples: application to sequence data

Rice University

Loley

Testing and Genetic Model Selection in Genome-Wide Association Studies

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck

Lorenzo Bermejo

Comparison of statistics of genetic association regarding the discrimination between causal variants and linked markers

University Hospital Heidelberg, Institute of Medical Biometry and Informatics

Luan

Genotype imputation and association testing using data from the 1000 Genomes Project

MRC Epidemiology Unit, Cambridge, UK

Lutz

A Nonparametric Approach to Population Based Association Tests

University of Colorado at Denver

Lyngdoh

Association between serum uric acid and adiposity markers: Mendelian randomization using SLC2A9 variants

Institute of Social and Preventive Medicine (IUMSP), University of Lausanne, Switzerland

Ma

Natural and Orthogonal Interaction framework for modeling GxG and GxE interactions

University of Texas M.D. Anderson Cancer Center

Mägi

Genome-wide association analysis of rare variants with Crohn’s disease

Wellcome Trust Centre for Human Genetics, University of Oxford

Müller-Myhsok

A new approach to prove involvement of a rare variant in disease susceptibility.

MPI Psychiatry

Macé

Genome-wide CNV association with Alzheimer and Parkinson disease with shared controls in France: a report of CNV-specific limitations.

Inserm UMR 1043, Univ. Paul Sabatier-Toulouse3, Centre de Physiopathologie de Toulouse-Purpan, Toulouse, France

Mahachie John

A robustness study to investigate the performance of parametric and non-parametric tests used in Model-Based Multifactor Dimensionality Reduction Epistasis Detection

Montefiore Institute and GIGA-Research (University of Liege)

Majumdar

A Computationally Fast Bayesian Semi-parametric Algorithm for Inferring Population Structure and Adjusting for Case-control Association Tests

Indian Statistical Institute

Makar

COX-2 (PTGS2) promoter variant increases risk of rectal cancer

Fred Hutchinson Cancer Research Center, Seattle, USA

Malik

DNA Repair Enzyme Genes and Congenital Heart Defects

University of Arkansas Medical Sciences

Mamasoula

AETIOLOGICAL ROLE OF FOLATE DEFICIENCY IN CONGENITAL CARDIOVASCULAR MALFORMATION: EVIDENCE FROM “MENDELIAN RANDOMISATION” AND META-ANALYSIS.

Institute of Genetic Medicine, Newcastle University UK

marenne

Copy number variant detection using SNP-chips: impact of calling performances on association tests

Inserm U946 / CNIO

Melton

UGT1A1 and serum bilirubin in American Indians: The Strong Heart Family Study

Texas Biomedical Research Institute

Minelli

Methods for meta-analyses of genome-wide association studies: critical assessment of empirical evidence

EURAC research

Montazeri

Systematic Meta-Analysis for Common Low Penetrance Genes in Colorectal Cancer

Ottawa University

Newcombe

Comparison of Methods for Evaluating the Predictive Benefit of Genetic Information for Prostate Cancer Risk

Genetics Division, GlaxoSmithKline Stevenage, SG1 2NY, UK

Nock

Integrating Multiple Genetic and Environmental Factors Using Structural Equation Modeling: An Application to Obesity, Adipokine and Cytokine Signaling Pathways and Prostate Cancer Risk

Case Western Reserve University

Nutsua

A comparison of CNV calling algorithms and analysis software

Institute of Clinical Molecular Biology

O'Brien

Bayesian approaches to identifying susceptibility loci: A simulation study

Gillings School of Global Public Health, University of North Carolina at Chapel Hill

Olsson

Pointwise-Haplotype Sharing Decomposition of Lod Scores In Association Analysis

Stockholm University, Department of Mathematics

Pütter

Does Size always Matter? A Simulation Study on the Impact of Slightly Altered True Genetic Models

Institute for Medical Informatics, Biometry and Epidemiology, University Duisburg-Essen, Essen, Germany

Patillon

Detecting signatures of recent positive selection at the VKORC1 gene locus

Inserm UMRS-946, Univ Paris Diderot, Paris, FranceUniv Paris Sud, Kremlin-Bicêtre and Univ Paris Sud, Kremlin-Bicêtre, France.

Pattaro

Genome-wide association studies (GWASs) in homogeneous subgroups of Caucasian samples identify six novel loci for renal function: the CKDGen Consortium

Institute of Genetic Medicine, European Academy of Bolzano/Bozen (EURAC)

Pedergnana

Linkage analysis of hepatitis C virus infection in an Egyptian population living in a highly endemic area

Inserm

Pinnaduwage

Integrating molecular (mRNA and miRNA) and immunohistochemical (IHC) data to identify subgroups of Estrogen Receptor (ER) positive breast cancer patients

Samuel Lunenfeld Research Institute

Poletta

Methodological approaches to evaluate teratogenic risk using birth defect registries: advantages and disadvantages.

ECLAMC (Latin American Collaborative Study of Congenital Anomalies) at CEMIC - CONICET

Poletta

Familial Relative Risks and Complex Segregation Analysis of Isolated Cleft Lip with or without Cleft Palate in a high-prevalence cluster of South America.

a) CEGEBI (Centro de Epidemiología Genética y Bioestadística) at CEMIC - CONICET; b) ECLAMC.

Preuβ

A new R package for the calculation of the exact CDF of Q and I² for meta-analyses

Institut für Medizinische Biometrie und Statistik

Rantalainen

Robust statistical methods for genome-wide eQTL analysis

Department of Statistics, University of Oxford

Roslin

Imputation accuracy in the MHC region based on 1000 Genomes data

The Hosptial for Sick Children

Ruczinski

Study design considerations to improve power in association tests for rare variants

Johns Hopkins University

Rudolph

Analysis of microsatellite markers: A comparison of four different ways to evaluate association with binary outcomes

Division of Cancer Epidemiology, German Cancer Research Center

saad

Hunting for rare susceptibility variants using in Genome-Wide-Association data of Parkinson’s disease

Inserm, UMR 1043

Satagopan

Properties of preliminary test and shrinkage estimators for evaluating multiple exposures

Memorial Sloan-Kettering Cancer Center

Schillert

Automated investigation of genotype calling using angles and tests for unimodality

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck

Schoof

Pathway analysis of the GenoMEL consortium genome-wide association study of melanoma: analysis of genes related to tumour immunosuppression

Department of Medical Epidemiology and Biostatistics, Karolinska Institute

Schwender

Fast Association Testing of Genotyped and Imputed SNPs as well as Gene-Environment Interactions in Case-Parent Trio Studies

TU Dortmund University

Sebro

A novel test for differentiating population stratification from genotyping error using family data

University of California, San Francisco, San Francisco, CA

Seibold

Polymorphisms in oxidative stress-related genes, radiotherapy, and overall survival in breast cancer patients – a replication study

German Cancer Research Center

Sheehan

Reconstructing Pedigrees from Genetic Marker Data

University of Leicester

Shrestha

DC-SIGN gene promoter polymorphisms in coronary artery disease and IVIG treatment outcomes in Hispanic Kawasaki disease (KD) patients

Dept of Epidemiology, University of Alabama at Birmingham

Siegert

Imputation-based genome-wide gene-environment interaction screening in colon cancer using a case-only design

Institute of Experimental Medicine

Siegmund

Preprocessing Illumina DNA Methylation BeadArrays

University of Southern California

Simpson

Covariate-based Linkage Analysis of Lung Cancer Risk Reveals Novel Loci on 9p21 and 20q12

National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland

Suktitipat

The Robustness of Generalized Estimating Equations for Association Tests in Extended Family Data

Genometrics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health

Sun

Epistatic Interactions among Genes with Known Evidence of Protein-Protein Interaction

Department of Epidemiology, Emory University

Sung

Analysis of Rare Genetic Variants in Family-based Sequence Data

Washington University in St Louis

Swartz

Searching through the folate metabolism pathway for genetic and nutritional risk factors for lung cancer.

University of Texas School of Public Health

Sylvestre

Genome-wide association studies of functional traits: an application to lipid density profiles in type 1 diabetes

CHUM Research Centre

Tachmazidou

Association testing for rare variants via pooled design

Wellcome Trust Sanger Institute

Teerlink

Significant confirmation of linkage to melanoma at 9q21 in an extended Utah pedigree

University of Utah

Tezenas du Montcel

Genetic susceptibility to language development and Attention-Deficit/Hyperactivity Disorder

Université Pierre et Marie Curie - Paris 6

Thomas

TWO-PHASE CASE-CONTROL STUDY DESIGN FOR BIOMARKER MEASUREMENTS IN GENE-ENVIRONMENT INTERACTIONS STUDIES

University of Southern California

Thompson

Plasma MicroRNAs in Breast Cancer Detection

Case Western Reserve University

Timofeeva

Meta-analysis of Genome-Wide Associations Studies of Lung Cancer

International Agency for Research on Cancer, France

Tsonaka

Gene-set testing on autosomes and sex chromosomes for complex phenotypes: An application in follow-up data for Rheumatoid Arthritis

Medical Statistics and Bioinformatics, Leiden University Medical Center

Tylavsky

Genetic and Epigenetic Analysis of Neonatal and Early Childhood Phenotypic Outcomes in a Community-Based Longitudinal Cohort in Memphis, TN: The CANDLE Study

University of Tennessee Health Science Center

Uh

Joint modeling of multiple biomarkers predicting longevity in families using weighted penalized logistic ridge (WPLR) regression

Dept. Medical Statistics and Bioinformatics, LUMC

van Duijn

Explaining the tails of quantitative distributions

ErasmusMC

Viktorova

Impact of Population Stratification on Gene-Environment Interaction Analysis

University Medical Center, Georg-August-University Göttingen, Germany

Wang

Selection of top SNPs for genome-wide association study using p values and magnitude of odds ratios

UT MD Anderson Cancer Center

Wang

Entropy based genetic association and gene-gene interaction tests

Mayo Clinic

Wang

A comparison of methods to detect complex trait rare variant associations implementing the RarePower tool

Baylor College of Medicine

Warren

Comparisons of shrinkage estimation methods for improved prediction of quantitative phenotypic traits related to individual CVD risk

London School of Hyigene & Tropical Medicine

Wijsman

Detection of Genotyping Errors in Dense Markers on Large Pedigrees

University of Washington

Winham

Interaction Detection with Random Forests in High-Dimensional Data

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic

Winkler

EasyGWA-S – A general software for stratified genome-wide association meta-analyses

Department of Epidemiology and Preventive Medicine, Regensburg University Medical Center, Regensburg, Germany

Wu

Whole-Genome Detection of Deletions Associated with Glioma in a Case-Control Study Using SNPs

Dept Epidemiology, M. D. Anderson Cancer Center

Yamada

Evaluation of power for linkage disequilibrium mapping

Statistical Genetics, Medicine, Kyoto University

Yang

Characterization of germ-line copy number variations in melanoma-prone families with and without CDKN2A/CDK4 mutations

Division of Cancer Epidemiology&Genetics, National Cancer Institute, NIH, DHHS

Yang

Boosting ensemble as a tool to combine genetic signals

Washington University School of Medicine

Yilmaz

Semiparametric maximum likelihood method for rare variant analysis under quantitative trait-dependent sampling designs

Samuel Lunenfeld Research Institute of Mount Sinai Hospital

Younkin

The Linkage Disequilibrium LASSO for SNP Selection in Genetic Association Studies

Case Western Reserve University

Zakharov

Cumulating association of risk-contributing and protective effects: a statistical test for rare variants

Genome Institute of Singapore

Zhang

Adjusting Relatedness in Family Data for Collapsing Association Test of Rare Variants

Washington University School of Medicine

Zhu

Detecting rare variants in admixed populations

Department of Epidemiology and Biostatistics, Case Western Reserve University