2005 Scientific Program

of the International Genetic Epidemiology Society

Sunday, October 23, 2005

Time 
Chairs / Speaker and Co-Authors

Abstract 

8:00 - 10:00

Computational Analysis

Chairs: M. de Andrade, P. Kraft

8:00

Welcome and Presidential Address

E.M. Wijsman

 

8:30

U-statistics for Testing the Association of Genotype Similarity with Trait Similarity: Methods for Quantitative and Censored Traits

D.J. Schaid, J.P. Sinnwell, S.N. Thibodeau

142

8:45

Multilocus Lod Scores in Large Pedigrees: A New Approach to Combine Exact and Approximate Calculations

L.Tong, E.A. Thompson

159

9:00

An Improved TREE Algorithm for Dissecting Complex Interacting Genetic Pathways

S. Howell, J.Wu, M.A. Province

77

9:15

A Flexible Data Mining Framework for Detecting and Interpreting Gene-Gene Interactions

J.H. Moore, J.C. Gilbert, C.-T. Tsai,

F.-T. Chiang, W. Holden, N. Barney,

B.C. White

122

9:30

Towards linkage analysis with linkage disequilibrium

Invited speaker: A. Thomas

 

 10:00 - 10:30  Break

 10:30 - 12:00

Neel and Williams Awards

Competition Finalists

Chairs: E.W. Daw, A. Ziegler
         
Neel Award
 

 

10:30

Coverage and Power in Genome-wide Association Studies

E. Jorgenson,  J. Witte

82

10:45

Evaluation and Comparison of Gene Clustering Methods in Microarray Analysis

A.Thalamuthu, I.Mukhopadhyay, X.Zheng, G.C.Tseng

156

11:00

Comparison of Methods for Estimating Admixture Background and Control for Population Stratification Confounding in Admixed Populations

H.J.T. Tsai, S. Choudhry, M. Naqvi,

W. Rodriguez-Cintron, E.G. Burchard, E. Ziv

160
 
Williams Award
 

 

11:15

Identification of Disease Susceptibility Loci Using a Co-Evolution Measure and Haplotype Phylogenies

C. Bardel,  P. Darlu,  E Génin

9

11:30

Missing Data in Association Studies: A Multiple Imputation Approach Applied to Case/Control and Family Data

P. Croiseau, E. Genin, H.J. Cordell

25

11:45

Searching for SNP Combinations Associated With Disease Susceptibility

B.-J. Feng, D.Goldgar, C.M. Van Duijn

47

12:00 - 1:30      Lunch [on your own]

1:30 - 3:30       Poster Session - Odd Numbered Abstracts

3:30 - 5:00
Applications

Chairs: R.C. Elston, I.R. König

3:30

Interpretation of a Combined Two-Point and Multipoint Linkage Statistic in the Genome Screening of a Multifactorial Disease

P. Margaritte-Jeannin, M.C. Babron,

F. Clerget-Darpoux

112

3:45

Determining Optimal Ratios of Affected to Unaffecteds in a Propensity Score Calculation to Maximize Power Gains for the Identification of the Lung Cancer 6q23-25 Linkage Peak

B.Q. Doan, D. Behnemann,

J.E. Bailey-Wilson, and the GELCC

34

4:00

Analysis of Admixture in Puerto Rican Women and Association of Admixture With Phenotypes

I. Halder, T. Frudakis, J. Fernandez,

M.D. Shriver

71

4:15

Development and Validation of a Risk Prediction Model for Pancreatic Cancer: PANCPRO

A.P. Klein, W. Wang, S. Chen,

G. Parmigiani

84

4:30

Consanguinity May Lower the Age of Onset of Nasopharyngeal Carcinoma in North African Populations

M. Corbex, W. Ben Ayoub, M. Khyatti,

S. Dahmoul, M. Ayad, F. Maachi,

W. Bedadra, M. Abdoun, S. Mesli,

M. Hamdi-cherif, K. Boualga, . Bouaouina,

L. Chouchane, A. Benider, F. Ben Ayed,

D.E. Goldgar.

24

4:45

Genome Wide Linkage Scan of 781 Affected Aibling Pair Families With Rheumatoid Arthritis Using the Illumina Linkage IV Set of ~5,600 SNP Markers.

C. I. Amos, W. Chen, A.T. Lee,

M.F. Seldin, L.A. Criswell, D.A. Kastner, E.F. Remmers, W. Li, M. Kern, P.K. Gregersen

4

5:00 - 6:00

 IGES Business Meeting

 

 

7:00                 Banquet

 

 

 

Monday, October 24, 2005

Time 

Chairs / Speaker and Co-Authors

Abstract

8:00 - 10:30

Ethics and Genetics,

New Statistical Methods

Chairs: D.C. Thomas, E.M. Wijsman

 8:00

Ethics and Genetics

Invited Speaker: B. M. Knoppers

 

8:30

Mendelian Randomisation and Instrumental Variables for Causal Inference

N.A. Sheehan, V. Didelez

146

8:45

Selection of SNPs for Evaluating Gene-Disease Associations Using Haplotypes

N. Li, M. Li

100

9:00

The Effect of Sample Size on Tagging SNP Performance and Consequences for Complex Disease Gene Mapping

E. Zeggini, W. Rayner, L. Cardon, M.I. McCarthy, on behalf of the International Type 2 Diabetes 1q Consortium

191

9:15

Multipoint Linkage Disequilibrium Mapping with Haplotype Block Structure

M. Zheng, M.S. McPeek

194

9:30

Strategy for Detecting Susceptibility Genes With Weak or no Marginal Effect

S. Kotti, F. Clerget-Darpoux

85

 9:45

Meta-Analyses of Correlated Genomic Scans

M.A. Province

137

10:00 - 10:30  Break

10:30 -12:00

Haplotypes and the HapMap Project

Chairs: E.W. Pugh, J.E. Bailey-Wilson

 10:30

HapMap

Invited Speaker: F. S. Collins

 

 11:00

Patterns of Linkage Disequilibrium are Conserved Within and Between Ethnic Groups: Sampling vs. Ancestry in the HapMap Project

F.C.L. Hyland, C.R. Scafe, H. Isaac,

F.M. De La Vega

80

 11:15

The Power of the Molecular Haplotype for the Study of Complex Diseases in Genetic Isolates

J.R. O’Connell

129

 11:30

On the Haplotype Uncertainty From Genotyping and Reconstruction Error and Its Impact on Association Analysis

C. Lamina, H. Küchenhoff, F. Bongardt,

B. Paulweber, F. Kronenberg,

H.-E. Wichmann, I.M. Heid

90

 11:45

The Effect of Marker Density on Haplotype Block Structure

Z. Yu, R. Guerra, H. H. Hobbs, J. C. Cohen

190

12:00 - 1:30 Lunch [on your own]

 1:30 - 3:00  Poster Session II - Even numbered Abstracts

 3:00 - 5:00

Genome-Wide Association Studies

Chairs: D.J. Schaid, M.A. Province

 3:00

Genome-Wide Association Scans for Prostate and Breast Cancer: Design and Analysis

P. Kraft, D. Hunter, S. Chanock, R. Hoover,

D. Gerhard, G. Thomas

86

 3:15

Recent Developments in Genome-Wide Association Scans

D.C. Thomas, J.D. Buckley, D.V. Conti,

W.J. Gauderman, J.P. Lewinger, D. O.Stram

157

 3:30

Genomic Screening in Family Based Association Testing and the Multiple Testing Problem

K. van Steen, M.B. McQueen, A. Herbert,

C. Rosenow, E.K. Silverman, N. M. Laird,

S.T. Weiss, C. Lange

164

 3:45

Coverage and Efficiency of Whole Genome Association Studies

J.C. Barrett, I. Pe'er, M.J. Daly, L.R. Cardon

11

 4:00

Effects of Single SNPs, Haplotypes, and Whole Genome LD Maps on Accuracy of Association Mapping

N. Maniatis, J. Gibson, S. Ennis, A. Collins,

N.E. Morton

111

 4:15

Seeing the Forest for the Trees in Genome-Wide Association Studies

J. Witte, E. Jorgenson

179

 4:30

Round Table on Genome-Wide Association Studies

 

 

 5:00

Adjourn